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Labcorp Oklahoma, Inc.
Test Directory


Index:

Cold Agglutinin Antibody

Order Name COLD AGG
Test Number: 5500450
Revision Date 07/10/2025
Test Name Methodology LOINC Code
Cold Agglutinin Antibody
Hemagglutination 5098-9 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 1 mL (0.5mL) Serum Clot Activator (SST or Red No-Gel) Refrigerated
Instructions Specimen: 1mL (0.5mL) Serum from Red-top tube or gel-barrier tube
Collection: Transport blood immediately to laboratory. Incubate at 37°C and allow to clot at 37°C. Separate serum from cells. If there is not a 37°C incubator, allow to clot at room temperature and separate serum from cells immediately after clotting.
Storage Requirements: Refrigerated
Storage Instructions: Do not refrigerate prior to separation of serum from red cells. Store separated serum in refrigerator.
Cause for Rejection: Refrigeration of the specimen before separating serum from cells
GENERAL INFORMATION
Expected TAT 3-4 Days  
Clinical Use Cold agglutinin disease must be considered for all patients with acquired hemolytic anemia who have a positive direct antiglobulin test. Also suspected for patients with chronic liver disease, certain viral infections and Mycoplasma pneumoniae infection. 
Performing Labcorp Test Code 006353 
CPT Code(s) 86157
Lab Section Reference Lab