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Labcorp Oklahoma, Inc.
Test Directory


Index:

Protein S, Functional

Order Name PROT S FUN
Test Number: 1506100
Revision Date 08/26/2014
Test Name Methodology LOINC Code
Protein S, Functional
Clot Detection 27822-6 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 5.4 mL Whole Blood Sodium Citrate 3.2% (Blue Top) Room Temperature
Alternate 1 3.0 mL Double Spun Plasma Sterile, Capped Plastic Tube Frozen
Instructions Please indicate anticoagulant therapy.
Collect Two 2.7mL Sodium Citrate 3.2% (Blue Top) tubes.

Each 2.7mL Sodium Citrate 3.2% (Blue Top) tube must be filled to the proper level, no hemolysis. Improperly filled tubes can give erroneous results. Whole blood must be transported to lab immediately.
If testing cannot be started within 4 hours of collection the specimen must be double spun then 1.5mL plasma aliquot from each tube into individual plastic aliquot tubes and freeze. 
Do not pool aliquots together!
GENERAL INFORMATION
Testing Schedule Tues, Thurs 
Expected TAT 2-4 Days  
Clinical Use Protein S has an essential anticoagulant function. A congenital or acquired deficiency of Protein S increases the risk of thrombo-embolism. Congenital deficiencies are divided into 3 types, based on levels of both total and free Protein S Antigen, and on the activity level of Protein S. Protein S can also be decreased in hepatic disorders, inflammatory syndromes and oral anticoagulant therapy. 
CPT Code(s) 85306
Lab Section Coagulation