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ALK-EML4 gene fusion by FISH

Order Name ALK FISH
Test Number: 9100787
Revision Date 06/19/2020
Test Name Methodology LOINC Code
ALK-EML4 gene fusion by FISH
Fluorescence in Situ Hybridization  
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred See Below Tissue Paraffin Block Room Temperature
Instructions Formalin fixed paraffin embedded tissue. Tissue source and block ID containing tumor are required on the requisition form.
Pathology permission is required for any alternate sample types.
GENERAL INFORMATION
Testing Schedule Tuesday, Thursday 
Expected TAT 7 Days  
Clinical Use Cinicial use: Rearrangements of the ALK (anaplastic large cell lymphoma) gene located at chromosome 2p23 is best detected by FISH analysis. Patients with lung adenocarcinoma carrying the ALK - EML4 gene fusion have been reported to have a good response to certain chemotherapeutic medications.
  
Notes Click here for Molecular Pre-Authorization information.
CPT Code(s) 88377
Lab Section Reference Lab