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Adenosine Deaminase, Pleural Fluid

Test Number: 3660750
Revision Date 11/17/2020
Test Name Methodology LOINC Code
Adenosine Deaminase, Pleural Fluid
Quantitative Spectrophotometry 35704-6 
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 0.5 mL (0.2 mL) Pleural Fluid Sterile Screwtop Container Frozen
Instructions Collect Pleural Fluid specimens in leak-proof container. Centrifuge specimen at room temperature.
Transfer 0.5mL(0.2mL) fluid to a Sterile Standard Transport Tube and Freeze
Specimen must remain frozen until received in lab. Indicate source on requisition.
Unacceptable Conditions: Serum, CSF, Whole blood. Bronchoalveolar lavage (BAL) specimens. Turbid specimens.
Stability: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month
Testing Schedule Sun, Tue, Thu 
Expected TAT 2-5 Days  
Clinical Use Adenosine deaminase (ADA) is an endogenous tissue enzyme which is released into the serum in patients with many different types of malignancies and infections, including viral hepatitis, infectious mononucleosis, typhoid fever, and tuberculosis. It is the most useful single test in portal hypertension (ascites) associated with liver cirrhosis. In pleural fluid, elevated ADA levels are very commonly associated with tuberculosis, although increased ADA activity may be found in effusions due to a number of causes, including TB, bacterial infections, rheumatologic disease, and lymphoproliferative disorders. In CSF, ADA is elevated in cases of tuberculous meningitis. 
Notes Reference Lab: ARUP
Test Code: 2006096
Click Here to view information on the ARUP website.
CPT Code(s) 84311
Lab Section Reference Lab