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Pheochromocytoma Evaluation

Test Number: 3630645
Revision Date 04/08/2021
Test Name Methodology LOINC Code
Catecholemine Total 24 Urine
HPLC/LCMSMS 16111-7 
Catecholemine/Creatinine Ratio 24 Urine
Calculation 43247-6 
Metanephrine Total 24 Urine
Metanephrine/Creatinine Ratio 24 Urine
Calculation 35644-4 
Creatinine, 24Hr Ur
Immunoassay (IA) / Kinetic Alkaline Picrate 2162-6 
[4182033] Total Volume
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 14 mL (5.5 mL) Urine, 24-hour 24 hour Urine Container Refrigerated
Instructions 14 mL 24-hour urine with 25 mL 6N HCl collected in a 24-hour urine container.
After urine collection, add 25 mL of 6N HCl to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and the sample is shipped frozen. Record 24-hour urine volume on test requisition and urine vial. Record patients age on test requisition and urine vial.
Patient Preparation NOTE: It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (aldomet), alpha blockers (dibenzyline) should be avoided 18-24 hours prior to specimen collection.
Specimen Stability: Room temperature 8 hours, Refrigerated 8 days, Frozen 30 days.
Reject Criteria: Received room temperature
Testing Schedule Mon-Fri 
Expected TAT 3-6 days  
Clinical Use Pheochromocytoma is a tumor of the adrenal gland associated with headaches, cyclic changes in blood pressure, sweating, and other symptoms. Pheochromocytomas produce catecholamines and metanephrine. 
Notes Reference Lab: Quest
Test Code: 10520X
Click Here to view information on the Quest website.
CPT Code(s) 82382; 82570; 83835
Lab Section Reference Lab