Anti-Neutrophil Cytoplasmic Antibody (ANCA)
					Order Name
					
						NEUT CY AB 
					
					
Test Number: 5565200
Revision Date 03/28/2022
				
			Test Number: 5565200
Revision Date 03/28/2022
| Test Name | Methodology | LOINC Code | 
|---|---|---|
| 
									
										
											Anti-Neutrophil Cytoplasm Titer
										
									 | 
								
									Indirect Fluorescent Antibody | 17351-8 | 
| 
									
										
											Anti-Neutrophil Cytoplasmic Pattern
										
									 | 
								
									Indirect Fluorescent Antibody | 49308-0 | 
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment | 
| Preferred | 1 mL | Serum | Clot Activator SST | Refrigerated or Frozen | 
| Instructions |  Separate serum from cells ASAP or within 2 hours of collection. Stability/Storage: Room Temperature: N/A, Refrigerated(2-8C): 48 hours, Frozen(-20C): 90 Days.  | 
							|||
| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Mon - Fri | 
| Expected TAT | 3 Days | 
| Clinical Use | ANCA is a family of autoantibodies with varied specificities. The 2 types of ANCA patterns are C- and P. C- and P- ANCA can be of considerable value in the diagnosis of the spectrum of vasculitis (e.g. Wegener's). Positive ANCA results presenting C-ANCA and P-ANCA will reflex to specific testing for MPO and/or PR-3 antibodies. An Atypical-P ANCA is associated with inflammatory bowel disease and will not reflex to MPO and/or PR-3 testing. | 
| CPT Code(s) | 86036 | 
| Lab Section | Immunology - Serology |